Gene name:
Caprin1 (G5E5;Gpiap;Gpiap1;Gpip137;M11s1;Rng105) ;
Protein name:
Caprin-1 ;
Alternative:
GPI-anchored membrane protein 1 ;Cytoplasmic activation- and proliferation-associated protein 1 ;Membrane component chromosome 11 surface marker 1 ;GPI-anchored protein p137 (GPI-p137;p137GPI) ;RNA granule protein 105 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Function:
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.
Subcellular Location:
Cytoplasm
cytosol
Cell projection
dendrite
Associated with RNA granules.
Protein Attributes:
50:
MPSATSHSGS | GSKSSGPPPP | SGSSGSEAAA | GAAAPASQHP | ATGTGAVQTE |
100:
AMKQILGVID | KKLRNLEKKK | GKLDDYQERM | NKGERLNQDQ | LDAVSKYQEV |
150:
TNNLEFAKEL | QRSFMALSQD | IQKTIKKTAR | REQLMREEAE | QKRLKTVLEL |
200:
QYVLDKLGDD | DVRTDLKQGL | SGVPILSEEE | LSLLDEFYKL | VDPERDMSLR |
250:
LNEQYEHASI | HLWDLLEGKE | KPVCGTTYKA | LKEIVERVFQ | SNYFDSTHNH |
300:
QNGLCEEEEA | ASAPTVEDQV | AEAEPEPAEE | YTEQSEVEST | EYVNRQFMAE |
350:
TQFSSGEKEQ | VDEWTVETVE | VVNSLQQQPQ | AASPSVPEPH | SLTPVAQSDP |
400:
LVRRQRVQDL | MAQMQGPYNF | IQDSMLDFEN | QTLDPAIVSA | QPMNPTQNMD |
450:
MPQLVCPQVH | SESRLAQSNQ | VPVQPEATQV | PLVSSTSEGY | TASQPLYQPS |
500:
HATEQRPQKE | PMDQIQATIS | LNTDQTTASS | SLPAASQPQV | FQAGTSKPLH |
550:
SSGINVNAAP | FQSMQTVFNM | NAPVPPANEP | ETLKQQSQYQ | ATYNQSFSSQ |
600:
PHQVEQTELQ | QDQLQTVVGT | YHGSQDQPHQ | VPGNHQQPPQ | QNTGFPRSSQ |
650:
PYYNSRGVSR | GGSRGARGLM | NGYRGPANGF | RGGYDGYRPS | FSNTPNSGYS |
700:
QSQFTAPRDY | SGYQRDGYQQ | NFKRGSGQSG | PRGAPRGRGG | PPRPNRGMPQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Mouse Caprin-1
ELISA Kit for Mouse Caprin-1
ELISA Kit for Mouse Caprin-1
ELISA Kit for Mouse Caprin-1
CLIA Kit for Mouse Caprin-1
CLIA Kit for Mouse Caprin-1
CLIA Kit for Mouse Caprin-1
CLIA Kit for Mouse Caprin-1
Polyclonal Antibody for Mouse Caprin-1
Polyclonal Antibody for Mouse Caprin-1
Polyclonal Antibody for Mouse Caprin-1
Polyclonal Antibody for Mouse Caprin-1
Monoclonal Antibody for Mouse Caprin-1
Monoclonal Antibody for Mouse Caprin-1
Monoclonal Antibody for Mouse Caprin-1
Monoclonal Antibody for Mouse Caprin-1
Protein for Mouse Caprin-1
Protein for Mouse Caprin-1
Protein for Mouse Caprin-1
Protein for Mouse Caprin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;PHOSPHORYLATION;MULTIMERIZATION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH G3BP1;SUBCELLULAR LOCATION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
4.
"Novel cDNA clone, G5E5, isolated from a mouse neonatal cerebellar library is expressed in a variety of adult and neonatal tissues."
Hodes M.E.
Submitted (1995-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6J-AW-J/AW-J X CBA/CAGNLE-A/A .
tissue :
Cerebellum .
5.
"RNA granule protein RNG105 deficiency impairs the dendritic localization of Na+/K+ ATPase subunit isoforms and synapse formation."
Shiina N.
,
Tokunaga M.
Submitted (2007-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
6.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-362
strain :
C57BL/6 .
tissue :
Embryo .
9.
"Novel cDNA clone, G5E5, maps to chromosome 16 and is expressed in a variety of adult and neonatal tissues."
Hodes M.E.
Submitted (1995-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 402-707
strain :
C57BL/6J-AW-J/AW-J X CBA/CAGNLE-A/A .
tissue :
Cerebellum .